Frequently asked questions
Is beta-alanine safe?
While this is not a frequently asked question, it should be. We understand many people care most about gaining muscle, looking great and performing at their best. But safety should not be overlooked. We believe it should actually be the first question asked when considering a new supplement, even before you question efficacy.
The answer to the safety question is a resounding YES. Studies, going up to 12 weeks of continued beta-alanine use, have looked at a large array of blood biochemical, hematological and hormonal markers and no negative changes have occurred whatsoever. While it is impossible to say beta-alanine is one hundred percent safe until longer term studies are complete, we do know that up to 12 weeks of continued beta-alanine supplementation is indeed safe.
Why not just take carnosine instead of beta-alanine?
When you ingest carnosine intact, most of it is broken down in the gastrointestinal (GI) tract into its constituent amino acids, beta-alanine and histidine. Some intact carnosine does escape the GI tract freely but even that amount is quickly broken down in our blood by the enzyme carnosinase. In a very short time, all the carnosine you just ingested is either eliminated or broken down into beta-alanine and histidine. These two amino acids are then taken into the muscle, where they are converted back into carnosine with the help of the enzyme carnosine synthetase.
Unfortunately, only about 40% of the carnosine you take actually contains beta-alanine, making it an inefficient source at best. You are better off, from both efficiency and a financial standpoint, taking beta-alanine directly. You would have to take substantially more carnosine just to approach the increased concentrations of carnosine
Shouldn’t I take extra histidine along with beta-alanine since histidine is a component of carnosine?
No, as histidine is already present in high concentrations in muscle, while beta-alanine is only present only in small amounts. Researchers have determined that it is beta-alanine that drives carnosine synthesis, not histidine. Since this has been proven repeatedly in research, there is no need to supplement with extra histidine to increase carnosine levels. There are potentially some select populations like vegans, vegetarians or the elderly that may not get enough histidine in their diets and are thus deficient, which may compromise optimal carnosine levels. But, we still don’t recommend taking just extra histidine with beta-alanine. Instead, we recommend these groups and simply bump up their total protein intake which will in turn solve their possible histidine deficiency. For the majority of healthy people, only beta-alanine is needed as histidine deficiency is rare and no extra supplementation is needed to increase carnosine concentrations.
Who can benefit from beta-alanine?
1. Individuals participating in weight training looking to gain muscle mass and increase strength.
2. Any individual involved in athletic activities where strength,power and muscular endurance are needed
3. Exercise enthusiasts who have reached a training plateau and are looking for a supplement to take them to the next level
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